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J S de Bono Selected Research

Carboplatin (JM8)

6/2010A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours.

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J S de Bono Research Topics

Disease

33Prostatic Neoplasms (Prostate Cancer)
01/2020 - 10/2006
18Neoplasms (Cancer)
01/2019 - 02/2000
5Fatigue
02/2014 - 11/2007
4Disease Progression
01/2018 - 01/2009
3Neoplasm Metastasis (Metastasis)
03/2016 - 10/2011
2Ovarian Neoplasms (Ovarian Cancer)
01/2019 - 01/2018
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 03/2002
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 08/2014
2Inflammation (Inflammations)
04/2015 - 03/2014
2Pain (Aches)
09/2013 - 06/2000
2Peripheral Nervous System Diseases (PNS Diseases)
09/2013 - 05/2012
2Neutropenia
05/2012 - 06/2010
2Vomiting
04/2012 - 06/2010
2Pathologic Complete Response
08/2000 - 06/2000
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
01/2019
1Spinal Cord Compression
04/2015
1Diarrhea
02/2014
1Sclerosis
02/2014
1Edema (Dropsy)
02/2014
1Sarcopenia
07/2013
1Exanthema (Rash)
11/2012
1Nausea
04/2012
1Thrombocytopenia (Thrombopenia)
04/2012
1Carcinoma (Carcinomatosis)
10/2011
1Thrombocytopenia 3
06/2010
1Myalgia
06/2010
1Carcinogenesis
08/2008
1Kidney Neoplasms (Kidney Cancer)
03/2008
1Hypersensitivity (Allergy)
12/2004

Drug/Important Bio-Agent (IBA)

10abirateroneIBA
01/2018 - 03/2009
7Docetaxel (Taxotere)FDA Link
01/2018 - 11/2007
6Biomarkers (Surrogate Marker)IBA
01/2019 - 02/2009
6Abiraterone AcetateIBA
01/2018 - 04/2013
6AndrogensIBA
01/2018 - 10/2010
5Pharmaceutical PreparationsIBA
01/2018 - 10/2006
5Hormones (Hormone)IBA
01/2018 - 11/2007
4enzalutamideIBA
01/2020 - 01/2014
4Androgen Receptors (Androgen Receptor)IBA
04/2015 - 10/2010
2capivasertibIBA
01/2020 - 08/2014
2Prednisolone (Predate)FDA LinkGeneric
01/2018 - 06/2000
2Paclitaxel (Taxol)FDA LinkGeneric
01/2018 - 06/2010
2Indicators and Reagents (Reagents)IBA
01/2018 - 04/2015
2Prednisone (Sone)FDA LinkGeneric
04/2016 - 04/2013
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2016 - 09/2010
2Mitoxantrone (Novantrone)FDA LinkGeneric
04/2015 - 09/2013
2cabazitaxelFDA Link
04/2015 - 09/2013
2Biological ProductsIBA
11/2014 - 02/2009
2Monoclonal AntibodiesIBA
11/2014 - 12/2004
2Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
01/2014 - 03/2009
2Antineoplastic Agents (Antineoplastics)IBA
11/2012 - 02/2009
2taxaneIBA
05/2012 - 04/2012
2Cisplatin (Platino)FDA LinkGeneric
05/2001 - 06/2000
1TensinsIBA
01/2020
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2020
1olaparibIBA
01/2019
1talazoparibIBA
01/2019
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2019
1rucaparibIBA
01/2019
1PlatinumIBA
01/2019
1niraparibIBA
01/2019
1antiarrhythmic peptide (AAP)IBA
01/2018
1Mechanistic Target of Rapamycin Complex 1IBA
01/2018
1vistusertibIBA
01/2018
1Alkaline PhosphataseIBA
03/2016
1AlbuminsIBA
03/2016
1SteroidsIBA
04/2015
1PF-04605412IBA
11/2014
1Immunoglobulin G (IgG)IBA
11/2014
1IntegrinsIBA
11/2014
1CytokinesIBA
11/2014
1Adenosine Triphosphate (ATP)IBA
08/2014
1Gefitinib (Iressa)FDA Link
08/2014
1Analgesics (Analgesic Drugs)IBA
09/2013
1Creatine Kinase (Creatine Phosphokinase)IBA
11/2012
1eribulinFDA Link
05/2012
1Transaminases (Aminotransferases)IBA
04/2012
1sepantroniumIBA
04/2012
1Prostate-Specific Antigen (Semenogelase)IBA
04/2012
1SurvivinIBA
04/2012
1CreatinineIBA
01/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2010
1LigandsIBA
10/2010
1Hemoglobins (Hemoglobin)IBA
09/2010
1Thymidine Monophosphate (TMP)IBA
09/2010
1Epithelial Cell Adhesion MoleculeIBA
09/2010
1belinostatIBA
06/2010
1Carboplatin (JM8)FDA LinkGeneric
06/2010
1Histone Deacetylase InhibitorsIBA
01/2010
1romidepsin (FK228)FDA Link
01/2010
1TransferasesIBA
06/2008
1prenylIBA
06/2008
1AZD3409IBA
06/2008
1pertuzumabIBA
11/2007
1AntigensIBA
12/2004
1mAb-AR20.5IBA
12/2004

Therapy/Procedure

28Castration
01/2020 - 10/2006
15Therapeutics
01/2019 - 03/2002
12Drug Therapy (Chemotherapy)
01/2019 - 06/2000
1Prostatectomy (Retropubic Prostatectomy)
04/2009
1Musculoskeletal Manipulations (Manipulative Therapy)
03/2009